High Pressure Liquid Chromatography in Coatings Analysis

By Francis V. Acholla

High pressure liquid chromatography (HPLC) is an established standard analytical tool for the analysis of coatings and related materials. An extensive body of literature has been published in various analytical and related fields’ journals on HPLC methods. These meth­ods have been developed and used in the determination of small to very large molecules ranging from small organic impurities to polymer resins.

In addition, fundamentals of HPLC and related methods have also been extensively covered in the literature and the reader is en­couraged to review them as needed. The objective of this article focuses mainly on the appli­cations of HPLC and gel permeation chromatography (GPC) methods in the analysis of coatings.